The Atlantic Coast Line (ACL) Railroad Depot, now the Lake Wales Depot Museum, is a single-story masonry building with elements of the Mediterranean Revival style that characterized architectural design in Florida during the 1920s. The building was constructed of hollow tile, its exterior walls covered with smooth stucco, and its hip roof capped with the barrel tile common to buildings of its style.

The Depot Museum is the principal building in Lake Wales associated with the railroad that remains from the historic period. Its completion in 1928 marked the end of 1920s Boom Time development in Lake Wales. It is located at 325 S Scenic Highway.